Category Archives: Treatment Approaches

Introducing “Listening to Prozac”

By Peter D. Kramer
By Peter D. Kramer MD

Last year I bought this book for RM5 from the Popular RM5 book fiesta (by now you probably have realized that I bought a lot of books there, and yes you’re right, I do spend time to go through those non-fictions and try to pick some treasure!). It is written by an American psychiatrist.

This is really a book that I’d strongly recommend, to … certain people, like me – who know quite a bit about psychopharmacology, but not enough, not much about their history – who have seen how all those drugs are used practically and in day to day life, but not read much about the facts and dark stories behind them. It is an old book I have to say, but I learnt so much about the older generation anti-depressants (tricyclic like Imipramine, Monoamine Oxidase Inhibitors which is not so common these days) and those that I’m so familiar with, i.e. the SSRIs (e.g. Prozac (Fluoxetine)!).

It made me think a lot about how those so-called legal drugs are prescribed, used and misused, how it can change a person from the inside (personality! how they see themselves all their lives simply changed after they started the medicine!), how vague the definitions of psychiatric diagnosis are, how tiny the difference between well and unwell could be etc etc. It may not be a book for everyone, I’m sure some might fall asleep reading it, but it’s probably the first time I’m reading such old book (published in 1993 -before I attended elementary school :P, some updates in early 21st centuries at the back) but still get so astonished and learnt so much!

介紹書<實用催眠自助手冊>

去年九月在台灣研究和了解當地的催眠時選下了這本書(作者是中國人,目前在上海作心理諮商),台幣300, 忘了有沒有折扣。當時只是抱著學習一些催眠術語和”看看別人怎麼用中文催眠”,才買下這本書。

作者蔡丹妮
作者蔡丹妮

寫的非常簡潔,主要是值得提倡的自我催眠(self-hypnosis),對外行來說應該不太難懂,可惜卻不能做入門的書,因為完成沒有最基本的解除催眠的謎思與誤解(myths and misconception),對我而言這是再基本不過的(比如應該要有類似這樣的東西,讓讀者進行自我催眠前多瞭解催眠)。另外,因為我買下這本書是為了學習中文術語,所以也特別注重作者對這些字詞的翻譯(作者執業前在美國深造),不難發現很多詞的翻譯不太准確,前後不一。最後就是作者可能和我一樣,”意見比較多”(哈哈),在這麼小的一本書,有些部份一大段的在分享個人的想法和意見,讀起來實在有失專業… 總結來說對外行和內行都不是太實用,市場上也會有更適合的相關書。

Drug Use & Drug Abuse

More specifically, it is Psychiatric drug use VS Illicit drug abuse

If I have depression, or dysthymia, or an inability to experience pleasure (anhedonia), why do I need to take psychiatric drugs? I can take cocaine, amphetamine, heroin or opium too, they make me happy and feel high too. It reminded me of the patient who took his own life by jumping off from a building. He said gathering with his bunch of friends and taking those pills are his kind of pleasurable activities (case study here), just like women go shopping or people go gym. Yea, right, how about that? Take a few “pills” and I’m better?

Antidepressants like Prozac and Lexapro (the SSRIs) do not provide pleasure, it restores the capacity for pleasure. It is neither excitatory like cocaine nor satiating like heroin. The drug taker doesn’t crave Prozac and does not feel relief when it enters the system. The desired effect, a change in responsiveness to ordinary pleasures, occur gradually and is unrelated to the daily act of consuming the drug. So unlike cocaine which produces quick, strong but short-lasting “high”, people don’t “usually” get addicted to the SSRIs.

Drug addicts use stimulant drugs hoping to cope with intolerable feelings. Without medication, they may experience little enjoyment. Prescribed medication makes drug addicts who kick the street-drug habit feel less empty and better able to enjoy ordinary pleasures. For the addict, the hope is to enhance the ability to “postpone gratification”, something antidepressants may do by increasing the ability to imagine future pleasure. If and when ordinary pleasure becomes appealing (after a drug addict is treated with psychiatric medicine and begins to experience “ordinary pleasure”), it’s hoped that self-understanding and self-control will follow (no longer rely on illicit drugs to achieve “instant pleasure”).

So can we use anti-depressants (and some other medication) to treat stimulant drug addictions? I believe with a combination of behavioural therapies, and supports from the immediate family members, anti-depressants would work. But taking only anti-depressants without strong mental and motivation to quit and sufficient social supports is definitely not enough, not in long-term for sure.

Psychiatric Drug Abuse?

But anti-depressant drugs (focusing on SSRIs here) can also be abused. There are patients whose depression were treated with the SSRIs, once successfully weaned from the tablets, want to restart it, not because they are depressed, but because life seemed brighter when they were medicated. In psychiatry it’s a bit difficult to decide where treatment ends and depression starts again.. but doesn’t this seem a bit like taking illicit drugs? Same applies to people who take excessive anxiolytics (anti-anxiety drugs / tranquilisers) to make them calm and functional, how do we define when it’s legal psychiatric drug abuse?

There are people who feel more mentally sharp and agile, talk more fluently, and more socially confident when they are on anti-depressants, they continue to take it even when they don’t show any signs of depression at all. Unlike amphetamines which also make people more alert and productive but at the same time is addictive and causing paranoia, most of these SSRIs don’t lead to any significant side effects (and (if) any discomfort tend to go away after first few days). So does this make it morally and ethically fine to take anti-depressants to increase alertness, quickness of thought, and verbal and mechanical fluency, in the absence of illness?

 

P.S. SSRIs stands for Selective Serotonin Reuptake Inhibitors, which are newer drugs used to treat depression, but also work for OCD and anxiety disorders. Some commonly used in Malaysia include Lexapro (Escitalopram), Prozac (Fluoxetine), Zoloft (Sertraline), Luvox (Fluvoxamine).

N.B. This post focuses more on major and minor depression, dysthymia and anhedonia.

Intervention Programmes for Autism in Malaysia

It just happened that I was doing a brief research on the internet and among my friends who are in the field, so here is some information that might be useful to those who are looking for early intervention programmes for children diagnosed with Autism. (It is up-to-date on April 2016, within Klang Valley only).

I’d advise to take your child and visit the centre, get a feel of how it’s like on a typical day, on top of enquiring what they offer and how they charge. If possible, bring someone who knows a bit more in the field!

  • Autism Link, Petaling Jaya (www.autism.my)
    • Using Applied Behavioural Analysis (ABA), 1:1 individually tailored
    • Parental training weekly
    • Monday – Friday (3 hours class)
    • Morning RM5500/month; Afternoon 4800/month; Full day 8500/month
    • Contact: 016-6100309 / 03-7957 0795; Email: enquiry@autism.my
    • According to a ABA therapist friend who used to work there, this centre is strongly recommendable if parents/family is financially capable.
  • Hatching, Jaya One, Petaling Jaya (www.HatchingCenter.com)
    • Modified ABA, 1:4 group (1 teacher/therapist, 4 children)
    • Workshop for parents/children monthly
    • 9am-12pm or 1pm-4pm RM1500/month; 9am-4pm RM2000/month
    • Make appointment for free pre-enrolment assessment (1 hour)
    • Contact: 011-1133 8518
  • ALRITE, USJ (www.alrite4kidz.com)
    • 3 hour or 6 hour session
    • Contact: 03- 8020 6666
    • I called up and was told that they don’t discuss the fee structures over the phone (it kind of makes me suspect …), to call up for appointment.
  • Bright Stars, Ara Damansara (www.brightstars.my)
    • Using ABA, the sun-rise programme; 1:1 or 1:2 individualised
    • 9am-12pm or 12:30pm-3:30pm, RM2900/month; 9am-3pm RM5200/month
    • Contact: 012-3222405 / 03-78590089
    • See brightstars.my/about_the_program (it appears to be the only centre that publishes their pricing online!)
  • The National Autism Society of Malaysia (NASOM) (www.nasom.org.my)
    • Many centres all over Malaysia, including one in Miri, Sarawak. One-stop assessment/diagnosis centre is at Setia Alam (603-3359 3987)
    • Star programme, 1:3
    • Monday-Friday 7.30am-12pm or 1pm-5pm (RM318/month, half day only)
    • May need to be put in waiting list but they have intake almost every month throughout the year
    • Note: The centre that I called up to enquire is Taman OUG centre (03-78317928 / 03-78327928)
  • Freelance ABA therapists
    • Usually much more affordable, so it would suit those family with financial constraint.
    • Some might be able to have sessions at home.
    • Standard, facility, materials used, quality, service might be compromised (or not!!)
    • It might be good to do a review (re-assessment) every 6 months or so to check the child’s progress
    • Where to find? Check the comment section below!

Disclaimer: I am in no way involved in any of the abovementioned centres and their therapists, I have not personally known anyone who had used their services so I cannot guarantee their service quality and outcome. I’m only providing different options to those who might need it, feel free to add your comments or recommend other centres below.

Taking psychiatric medication in long-term?

“Do I have to take these pills in long-term? Do I have to depend on them for the rest of my life?”

This is one common question asked in the psychiatric clinic, especially during their first visit when they are prescribed with medicine, and again especially so in the Asians, who seem never quite keen to take western medicine (including myself).

I believe different consultant psychiatrists have different response to this question. More commonly, the answer is either, “not in long-term, but you will have to maintain stably for few months” (so before you are stable, it’s not taken into consideration), or, “yes, that will be better for you; though you should be able to maintain on a minimal dosage” (for some people, maybe just half a tablet of Lexapro 10mg).

And then they will continue to throw you with more questions… But today I just want to focus on this first question. And please take note that I have a background in clinical psychology, not medicine, and I had worked in a national forensic psychiatric ward (UK) for 3 years then in a private psychiatric outpatient clinic (KL) for almost 3 years too. (For differences between psychology and psychiatry, please see here)

I’d advise that you seek advice from your consultant. But if for any reason, you need a second opinion or some reassurance, these are a few points that you can consider…

  1. Are you in a stable state now? Do you and your closed ones around you think you are well? How functional are you compared to the time before you become unwell? (It’s obvious, if you are not even stable on the medicine, do you think you will be fine without it?)
  2. Is this your first episode? (I don’t think any psychiatrist would advocate long-term antidepressant treatment for people who have had a single episode of major depression; It may be different for people with anxiety or psychotic related problems)
  3. If this is not your first episode, how close is this episode to the previous one? How severe is this episode? Is it getting harder to manage, to return to your ‘normal’ state? (The general pattern was a decrease in the interval between episodes and an increase in the severity and complexity of the episodes, until finally rapid cycling set in. As time passes, it requires ever smaller stimuli (e.g. stress, a bit of change, an argument) to trigger an episode. The latter recurrences would typically include all the symptoms of earlier episodes, plus additional symptoms. So, if there has been a number of episodes, and it seems to get harder to manage and cope, you are strongly recommended to continue with the medication instead of withdrawing)
  4. Any early traumatic or stressful life events, e.g. physical/sexual abuse, separation from main carer, death of a parent, prolonged hospitalisation, marital quarreling, mental illness in a family member etc when you were young? (Those are not just memories, the incidents could also have altered your brain, leaving it more susceptible/vulnerable to stress, separation, rejection, loss etc. Click here for more details. Anti-depressant medications have been found to prevent further neural damage and block cell loss.)
  5. Are you someone who’s very sensitive and/or easily stressed? (It might suggest a vulnerability originated from the brain, please refer to 4.)
  6. Are you doing any psychotherapy? Are you responding to it? Does it help? (Not everyone responds well to psychotherapy. But as a psychologist and a psychotherapist I will have to add this point to the list! It is always good to learn more about the illness, to spot the early signs of relapse, to cope with stress and adversities in life etc. How can psychotherapy help after one’s stable with psychiatric medication? I have a post here in Chinese that explains it.)

Again I would like to emphasise the importance to discuss this with your consultant, whether you have financial difficulties, or maybe you think you are stable enough to stop or reduce, or maybe you think psychotherapy will help you in long-term. Sometimes it’s not a bad idea to have a second opinion, but that’s after sticking to one consultant long enough (a few months at least) and things still never improve.

 

A few readings that is related to the topic:

The need to maintain on psychiatric medicine (psychotic and related illness)

The more you worry about having to take medicine, the more you need to take them

Is psychotherapy for me? (Well, if you are now stable and really are not keen to continue with medicine, check here to see if psychotherapy may be for you)

Anti-depressant & Anti-anxiety Medicine (Maybe you are thinking to try to reduce some medicine without the advice from your consultant? See this first)

精神藥物的角色 (The role of psychiatric medication, in Chinese. It also tells you the role of psychotherapy after you are maintaining well on medicine)

In the news: Mum killed for asking son to take psychiatric medicine (No, don’t force them. If they are not willing to take the medicine, try to get professional advice to see what you can do to help, but don’t make them take it…)

Psychology Today: 7 ways childhood adversity can change your Brain (How those adverse experience make you more vulnerable…)

Introducing “Your Medical Mind: How to Decide what is Right for you”

By Jerome Groopman MD & Pamela Hartzband MD

By Jerome Groopman MD & Pamela Hartzband MD

I bought this book for from the Popular RM 5 fiesta last year. In a way it’s not directly related to psychology or mental health, but in fact anything about human behaviour – it is psychology. And this book is about how patients decide their treatments.

It doesn’t tell you how to decide, or what is right for you, but it shows you clearly how your past experience and up bringing influence your attitudes and decisions. I’d say this is important to know (I’m a minimalist, and a serious doubter), so I learnt how to communicate with my doctors, so that I see how the dr’s background may affect his/her approach on the patients, so I can help the dr to help me better. In addition to that, I also learnt how to understand those figures that drs or papers like to present us with, it is an important skill to gain (so when the dr tells you taking X drug will help 30% of the patients who are similar to you, you know what it really means).

Few things that I learnt from the book:

  •  When you feel good, it’s difficult to imagine the choices and to forecast the decisions you will make when you are ill. Imagining that you have a disease, or that you have to live with X side effects, is not the same as actually experiencing them.
  • All of us initially overestimate the ultimate impact of illness and its unpleasant side effects because we tend to focus on the negative and neglect the numerous positives in our lives.
  • Many psychological studies show that we regularly underestimate our ability to adapt.
  • Much of medicine is still an uncertain science, existing in gray zone — not clearly black or white. So there isn’t a clear “best” approach.
  • Bernoulli’s Formula [(probability of outcome) x (utility of outcome) = expected utility]
  • Three approaches that researchers have devised to come up with a number for the impact of living with a side effect: (1) rating scale; (2) time trade-off; (3) standard gamble. (please see the book for details, but they are not interchangeable, so I don’t consider them as practical.)
  • A doctor’s good reputation can be built by … simply picking healthier patients, and avoiding patients with multiple medical problems (such as diabetes with kidney failure and heart disease), and thus will have better “outcomes”.
  • A person’s wishes about treatment often fluctuate over the course of an illness. Completing a living will or advance directive had no effect on whether they maintained or shifted their initial thoughts about what therapies they wanted. It is difficult to imagine what they will want and how much they can endure when their condition shifts from healthy to sick and then to even sicker.
  • Modern technology can support, at least temporarily, organs like lungs with a ventilator, the heart with a bypass apparatus, and the kidneys with dialysis. The liver cannot be supported by a machine but this vital organ can be transplanted.
  • Research among patients in the ICU found that doctors are generally correct in giving a prognosis for moderately ill patients, but they aren’t very good at predicting the course of the sickest patients. They erred on both sides — too optimistic and too pessimistic.
  • And many more…